Description
Product Characteristics:
Spindly/CCDC99
Subcellular location: Cytoplasm, Nucleus
Synonyms: Rrhabdomyosarcoma antigen protein MU RMS 40.4A, Arsenite related gene 1 protein, Arsenite-related gene 1 protein, CCDC 99, Ccdc99, Coiled coil domain containing 99, Coiled-coil domain-containing protein 99, hSpindly, Protein Spindly, rhabdomyosarcoma antigen MU RMS 40.4A, Rhabdomyosarcoma antigen MU-RMS-40.4A, SPDLY_HUMAN, Spindly.
Target Information: Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex (By similarity)